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The hypoxia-inducible-factor hydroxylases bring fresh air into hypoxia signalling
Metazoans rapidly respond to changes in oxygen availability by regulating gene expression. The transcription factor hypoxia-inducible-factor (HIF), which controls the expression of several genes, ‘senses' the oxygen concentration indirectly through the hydroxylation of two proline residues that...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2006
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1369233/ https://ncbi.nlm.nih.gov/pubmed/16391536 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400598 |
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