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Cross-talk between the mechano-gated K(2P) channel TREK-1 and the actin cytoskeleton

TREK-1 (KCNK2) is a K(2P) channel that is highly expressed in fetal neurons. This K(+) channel is opened by a variety of stimuli, including membrane stretch and cellular lipids. Here, we show that the expression of TREK-1 markedly alters the cytoskeletal network and induces the formation of actin- a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lauritzen, Inger, Chemin, Jean, Honoré, Eric, Jodar, Martine, Guy, Nicolas, Lazdunski, Michel, Jane Patel, Amanda
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1369110/
https://ncbi.nlm.nih.gov/pubmed/15976821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400449
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