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Desensitization of mechano-gated K(2P) channels
The neuronal mechano-gated K(2P) channels TREK-1 and TRAAK show pronounced desensitization within 100 ms of membrane stretch. Desensitization persists in the presence of cytoskeleton disrupting agents, upon patch excision, and when channels are expressed in membrane blebs. Mechanosensitive currents...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1458984/ https://ncbi.nlm.nih.gov/pubmed/16636285 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0600463103 |
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