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Genetic redundancy masks diverse functions of the tumor suppressor gene PTEN during C. elegans development
Genetic redundancy is associated with a large percentage of genes. We investigated PTEN (phosphatase and tensin homolog deleted on chromosome 10) tumor suppressor gene functions that eluded single mutant analyses, using a Caenorhabditis elegans genome-wide screen. We show that at least 27 genes coll...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2006
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1369044/ https://ncbi.nlm.nih.gov/pubmed/16481471 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1378906 |
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