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Further insight into the stereoselective interaction between warfarin and cimetidine in man.

The urinary profile of R- and S-warfarin, following administration of a single (25 mg) oral dose of racemic warfarin, alone or on day 4 of a 9-day chronic administration of cimetidine (800 mg once daily), was investigated in eight healthy male volunteers. Based on estimated apparent formation cleara...

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Main Authors: Niopas, I, Toon, S, Rowland, M
Format: Artigo
Jezik:Inglês
Izdano: 1991
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1368615/
https://ncbi.nlm.nih.gov/pubmed/1958448
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