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Cimetidine-nicoumalone interaction in man: stereochemical considerations.

1. The cimetidine-nicoumalone interaction was studied in five subjects who received a single 10 mg oral dose of racemic nicoumalone alone and 3 days into an oral regimen of cimetidine of 200 mg three times daily and 400 mg at night. 2. The concentrations of R(+)- and S(-)-nicoumalone in plasma were...

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Detalhes bibliográficos
Main Authors: Gill, T S, Hopkins, K J, Bottomley, J, Gupta, S K, Rowland, M
Formato: Artigo
Idioma:Inglês
Publicado em: 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1379726/
https://ncbi.nlm.nih.gov/pubmed/2719902
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