The effect of various drugs on the glucuronidation of zidovudine (azidothymidine; AZT) by human liver microsomes.

1. Zidovudine (3'-azido-3'-deoxythymidine; AZT) is the drug of proven efficacy available for the treatment of patients with AIDS or ARC. It is eliminated mainly by hepatic glucuronidation. Therefore, interference with this metabolic pathway may lead to enhancement of AZT effect or to incre...

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Detaylı Bibliyografya
Asıl Yazarlar: Sim, S M, Back, D J, Breckenridge, A M
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1991
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1368487/
https://ncbi.nlm.nih.gov/pubmed/1909542
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