The effect of various drugs on the glucuronidation of zidovudine (azidothymidine; AZT) by human liver microsomes.

1. Zidovudine (3'-azido-3'-deoxythymidine; AZT) is the drug of proven efficacy available for the treatment of patients with AIDS or ARC. It is eliminated mainly by hepatic glucuronidation. Therefore, interference with this metabolic pathway may lead to enhancement of AZT effect or to incre...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Sim, S M, Back, D J, Breckenridge, A M
Formato: Artigo
Lenguaje:Inglês
Publicado: 1991
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1368487/
https://ncbi.nlm.nih.gov/pubmed/1909542
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares