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Diflunisal and its conjugates in patients with renal failure.

Six patients with renal failure were given a single oral dose (250 mg) of diflunisal. In contrast to the acyl glucuronide, the phenolic glucuronide and sulphate conjugates showed the capacity to accumulate in plasma, suggesting that systemic instability of the acyl glucuronide contributes, via hydro...

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Bibliografiske detaljer
Main Authors: Dickinson, R G, Verbeeck, R K, King, A R, Restifo, A C, Pond, S M
Format: Artigo
Sprog:Inglês
Udgivet: 1991
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1368474/
https://ncbi.nlm.nih.gov/pubmed/1888623
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