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Diflunisal and its conjugates in patients with renal failure.

Six patients with renal failure were given a single oral dose (250 mg) of diflunisal. In contrast to the acyl glucuronide, the phenolic glucuronide and sulphate conjugates showed the capacity to accumulate in plasma, suggesting that systemic instability of the acyl glucuronide contributes, via hydro...

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Detalhes bibliográficos
Main Authors: Dickinson, R G, Verbeeck, R K, King, A R, Restifo, A C, Pond, S M
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1368474/
https://ncbi.nlm.nih.gov/pubmed/1888623
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