CD4 T Cells Are the Only Lymphocytes Needed To Protect Mice against Rotavirus Shedding after Intranasal Immunization with a Chimeric VP6 Protein and the Adjuvant LT(R192G)

Intranasal immunization of mice with a chimeric VP6 protein and the mucosal adjuvant Escherichia coli heat labile toxin LT(R192G) induces nearly complete protection against murine rotavirus (strain EDIM [epizootic diarrhea of infant mice virus]) shedding for at least 1 year. The aim of this study wa...

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Vydáno v:	J Virol
Hlavní autoři:	McNeal, Monica M., VanCott, John L., Choi, Anthony H. C., Basu, Matili, Flint, Jason A., Stone, Susan C., Clements, John D., Ward, Richard L.
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 2002
Témata:	Vaccines and Antiviral Agents
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136815/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11752147/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.2.560-568.2002
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CD4 T Cells Are the Only Lymphocytes Needed To Protect Mice against Rotavirus Shedding after Intranasal Immunization with a Chimeric VP6 Protein and the Adjuvant LT(R192G)

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