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Differential Interaction of Cardiac, Skeletal Muscle, and Yeast Tropomyosins with Fluorescent (Pyrene(235)) Yeast Actin

To monitor binding of tropomyosin to yeast actin, we mutated S(235) to C and labeled the actin with pyrene maleimide at both C(235) and the normally reactive C(374). Saturating cardiac tropomyosin (cTM) caused about a 20% increase in pyrene fluorescence of the doubly labeled F-actin but no change in...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Chen, Weizu, Wen, Kuo-Kuang, Sens, Ashley E., Rubenstein, Peter A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Biophysical Society 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1367282/
https://ncbi.nlm.nih.gov/pubmed/16326906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.064634
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