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Apyrase, the Product of the Virulence Plasmid-Encoded phoN2 (apy) Gene of Shigella flexneri, Is Necessary for Proper Unipolar IcsA Localization and for Efficient Intercellular Spread
The role in virulence of the Shigella flexneri ospB-phoN2 operon has been evaluated. Here we confirm that OspB is an effector and show that apyrase, the product of phoN2, may be a virulence factor, since it is required for efficient intercellular spreading. Apyrase may be important in a deoxynucleos...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1367242/ https://ncbi.nlm.nih.gov/pubmed/16452446 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.188.4.1620-1627.2006 |
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