Shigella flexneri DegP Facilitates IcsA Surface Expression and Is Required for Efficient Intercellular Spread

A degP mutant of Shigella flexneri was identified in a screen for insertion mutants that invaded cultured cells but did not form wild-type plaques in monolayers. The degP mutant SM1100 invaded Henle cells at wild-type levels and induced apoptosis in macrophages but formed smaller plaques than those...

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Bibliographic Details
Main Authors: Purdy, Georgiana E., Hong, Mei, Payne, Shelley M.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2002
Subjects:
Molecular Pathogenesis
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC130383/
https://ncbi.nlm.nih.gov/pubmed/12379715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.11.6355-6364.2002
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