Efficient Site-Specific Integration of Large Transgenes by an Enhanced Herpes Simplex Virus/Adeno-Associated Virus Hybrid Amplicon Vector

We previously demonstrated that a herpes simplex virus type 1 (HSV-1)/adeno-associated virus (AAV) hybrid amplicon vector constructed by inserting the sequences of regulatory protein (rep) and inverted terminal repeats of AAV into an HSV amplicon vector resulted in the enhanced stability of transgen...

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Detalhes bibliográficos
Main Authors: Liu, Qiang, Perez, Claudio F., Wang, Yaming
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Gene Delivery
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1367150/
https://ncbi.nlm.nih.gov/pubmed/16439524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.4.1672-1679.2006
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