Efficient Site-Specific Integration of Large Transgenes by an Enhanced Herpes Simplex Virus/Adeno-Associated Virus Hybrid Amplicon Vector

We previously demonstrated that a herpes simplex virus type 1 (HSV-1)/adeno-associated virus (AAV) hybrid amplicon vector constructed by inserting the sequences of regulatory protein (rep) and inverted terminal repeats of AAV into an HSV amplicon vector resulted in the enhanced stability of transgen...

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Bibliographische Detailangaben
Hauptverfasser: Liu, Qiang, Perez, Claudio F., Wang, Yaming
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2006
Schlagworte:
Gene Delivery
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1367150/
https://ncbi.nlm.nih.gov/pubmed/16439524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.4.1672-1679.2006
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