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Regulation of Human Papillomavirus Type 16 E7 Activity through Direct Protein Interaction with the E2 Transcriptional Activator

In order to ensure a productive life cycle, human papillomaviruses (HPVs) require fine regulation of their gene products. Uncontrolled activity of the viral oncoproteins E6 and E7 results in the immortalization of the infected epithelial cells and thus prevents the production of mature virions. Ecto...

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Detalhes bibliográficos
Main Authors: Gammoh, Noor, Grm, Helena Sterlinko, Massimi, Paola, Banks, Lawrence
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1367139/
https://ncbi.nlm.nih.gov/pubmed/16439535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.4.1787-1797.2006
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