Modulation of Cellular Protein Trafficking by Human Immunodeficiency Virus Type 1 Nef: Role of the Acidic Residue in the ExxxLL Motif

The nef gene contributes to the replication of primate lentiviruses by altering the trafficking of cellular proteins involved in adaptive immunity (class I and II major histocompatibility complex [MHC]) and viral transmission (CD4 and DC-SIGN). A conserved acidic leucine-based sequence (E(160)xxxLL)...

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Main Authors: Coleman, Scott H., Madrid, Ricardo, Van Damme, Nanette, Mitchell, Richard S., Bouchet, Jerome, Servant, Cecile, Pillai, Satish, Benichou, Serge, Guatelli, John C.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2006
主題:
Virus-Cell Interactions
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1367136/
https://ncbi.nlm.nih.gov/pubmed/16439540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.4.1837-1849.2006
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