Modulation of Cellular Protein Trafficking by Human Immunodeficiency Virus Type 1 Nef: Role of the Acidic Residue in the ExxxLL Motif

The nef gene contributes to the replication of primate lentiviruses by altering the trafficking of cellular proteins involved in adaptive immunity (class I and II major histocompatibility complex [MHC]) and viral transmission (CD4 and DC-SIGN). A conserved acidic leucine-based sequence (E(160)xxxLL)...

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Detalhes bibliográficos
Main Authors: Coleman, Scott H., Madrid, Ricardo, Van Damme, Nanette, Mitchell, Richard S., Bouchet, Jerome, Servant, Cecile, Pillai, Satish, Benichou, Serge, Guatelli, John C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1367136/
https://ncbi.nlm.nih.gov/pubmed/16439540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.4.1837-1849.2006
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