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Φ-Value Analysis of a Linear, Sequential Reaction Mechanism: Theory and Application to Ion Channel Gating
We derive the analytical form of a rate-equilibrium free-energy relationship (with slope Φ) for a bounded, linear chain of coupled reactions having arbitrary connecting rate constants. The results confirm previous simulation studies showing that Φ-values reflect the position of the perturbed reactio...
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| Päätekijät: | , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Biophysical Society
2005
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1366938/ https://ncbi.nlm.nih.gov/pubmed/16183877 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.067215 |
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