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Mutations Conferring Aminoglycoside and Spectinomycin Resistance in Borrelia burgdorferi

We have isolated and characterized in vitro mutants of the Lyme disease agent Borrelia burgdorferi that are resistant to spectinomycin, kanamycin, gentamicin, or streptomycin, antibiotics that target the small subunit of the ribosome. 16S rRNA mutations A1185G and C1186U, homologous to Escherichia c...

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Detalhes bibliográficos
Main Authors: Criswell, Daniel, Tobiason, Virginia L., Lodmell, J. Stephen, Samuels, D. Scott
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1366916/
https://ncbi.nlm.nih.gov/pubmed/16436695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.50.2.445-452.2006
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