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Mutations Conferring Aminoglycoside and Spectinomycin Resistance in Borrelia burgdorferi

We have isolated and characterized in vitro mutants of the Lyme disease agent Borrelia burgdorferi that are resistant to spectinomycin, kanamycin, gentamicin, or streptomycin, antibiotics that target the small subunit of the ribosome. 16S rRNA mutations A1185G and C1186U, homologous to Escherichia c...

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Détails bibliographiques
Auteurs principaux: Criswell, Daniel, Tobiason, Virginia L., Lodmell, J. Stephen, Samuels, D. Scott
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2006
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1366916/
https://ncbi.nlm.nih.gov/pubmed/16436695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.50.2.445-452.2006
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