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Pharmacokinetic-Pharmacodynamic Comparison of Amphotericin B (AMB) and Two Lipid-Associated AMB Preparations, Liposomal AMB and AMB Lipid Complex, in Murine Candidiasis Models

It is generally accepted that the lipid formulations of amphotericin B (AMB) are not as potent as conventional AMB on a milligram-per-kilogram basis. We used a neutropenic murine disseminated candidiasis model to compare the in vivo potencies of AMB, liposomal AMB (L-AMB), and AMB lipid complex (ABL...

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Bibliografiset tiedot
Päätekijät: Andes, D., Safdar, N., Marchillo, K., Conklin, R.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2006
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1366906/
https://ncbi.nlm.nih.gov/pubmed/16436726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.50.2.674-684.2006
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