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Attaching Single Biomolecules Selectively to the Apex of AFM Tips for Measuring Specific Interactions

We present a general approach for preparing well-defined AFM tips for probing single target molecules. We demonstrated that carboxylic acid groups could be generated by electrochemical oxidation selectively at the apex of an AFM tip that is coated with a monolayer of oligo(ethylene glycol) derivativ...

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Detalhes bibliográficos
Main Authors: Gu, Jianhua, Xiao, Zhongdang, Yam, Chi-Ming, Qin, Guoting, Deluge, Maxence, Boutet, Sabine, Cai, Chengzhi
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1366859/
https://ncbi.nlm.nih.gov/pubmed/16199511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.069104
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