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Attaching Single Biomolecules Selectively to the Apex of AFM Tips for Measuring Specific Interactions

We present a general approach for preparing well-defined AFM tips for probing single target molecules. We demonstrated that carboxylic acid groups could be generated by electrochemical oxidation selectively at the apex of an AFM tip that is coated with a monolayer of oligo(ethylene glycol) derivativ...

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Bibliografiske detaljer
Main Authors: Gu, Jianhua, Xiao, Zhongdang, Yam, Chi-Ming, Qin, Guoting, Deluge, Maxence, Boutet, Sabine, Cai, Chengzhi
Format: Artigo
Sprog:Inglês
Udgivet: Biophysical Society 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1366859/
https://ncbi.nlm.nih.gov/pubmed/16199511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.069104
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