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The Catalytic Copper of Peptidylglycine α-Hydroxylating Monooxygenase also Plays a Critical Structural Role
Many bioactive peptides require amidation of their carboxy terminus to exhibit full biological activity. Peptidylglycine α-hydroxylating monooxygenase (PHM; EC 1.14.17.3), the enzyme that catalyzes the first of the two steps of this reaction, is composed of two domains, each of which binds one coppe...
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| Główni autorzy: | , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Biophysical Society
2005
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1366827/ https://ncbi.nlm.nih.gov/pubmed/16100265 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.066100 |
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