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Tight Binding of Influenza Virus Hemagglutinin to Its Receptor Interferes with Fusion Pore Dilation

Deletion of oligosaccharide side chains near the receptor binding site of influenza virus A/USSR/90/77 (H1N1) hemagglutinin (HA) enhanced the binding of HA to erythrocyte receptors, as was also observed with A/FPV/Rostock/34 (H7N1). Correlated with the enhancement of binding activity, the cell fusio...

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Autores principales: Ohuchi, Masanobu, Ohuchi, Reiko, Sakai, Tatsuya, Matsumoto, Akira
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2002
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC136675/
https://ncbi.nlm.nih.gov/pubmed/12438566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.24.12405-12413.2002
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