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Cholesterol Dictates the Freedom of EGF Receptors and HER2 in the Plane of the Membrane

The flow of information through the epidermal growth factor receptor (EGFR) is shaped by molecular interactions in the plasma membrane. The EGFR is associated with lipid rafts, but their role in modulating receptor mobility and subsequent interactions is unclear. To investigate the role of nanoscale...

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Main Authors: Orr, Galya, Hu, Dehong, Özçelik, Serdar, Opresko, Lee K., Wiley, H. Steven, Colson, Steven D.
Format: Artigo
Jezik:Inglês
Izdano: Biophysical Society 2005
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Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1366621/
https://ncbi.nlm.nih.gov/pubmed/15908575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.056192
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