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HER2-Mediated Effects on EGFR Endosomal Sorting: Analysis of Biophysical Mechanisms

Overexpression of HER2, a receptor-like tyrosine kinase and signaling partner for the epidermal growth factor receptor (EGFR), has been implicated in numerous experimental and clinical studies as promoting the progression of many types of cancer. One avenue by which HER2 overexpression may dysregula...

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Detalhes bibliográficos
Main Authors: Hendriks, Bart S., Wiley, H. Steven, Lauffenburger, Douglas
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1303497/
https://ncbi.nlm.nih.gov/pubmed/14507736
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