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Sorting Out the Role of α-Synuclein in Retromer-Mediated Endosomal Protein Sorting
Retromer is a phylogenetically conserved, multisubunit coat complex that controls endosomal protein trafficking and sorting. Mutations in the retromer gene VPS35 cause late-onset Parkinson disease, suggesting that trafficking defects cause neurodegeneration. Sorting nexins assist retromer to guide c...
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| Publicado en: | J Exp Neurosci |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
SAGE Publications
2018
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6109851/ https://ncbi.nlm.nih.gov/pubmed/30158827 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1179069518796215 |
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