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Topoisomerase IV Bends and Overtwists DNA upon Binding

Escherichia coli topoisomerase IV (Topo IV) is an essential ATP-dependent enzyme that unlinks sister chromosomes during replication and efficiently removes positive but not negative supercoils. In this article, we investigate the binding properties of Topo IV onto DNA in the absence of ATP using a s...

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Sonraí Bibleagrafaíochta
Main Authors: Charvin, G., Strick, T. R., Bensimon, D., Croquette, V.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Biophysical Society 2005
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1366538/
https://ncbi.nlm.nih.gov/pubmed/15863484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.060202
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