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Topoisomerase IV Bends and Overtwists DNA upon Binding
Escherichia coli topoisomerase IV (Topo IV) is an essential ATP-dependent enzyme that unlinks sister chromosomes during replication and efficiently removes positive but not negative supercoils. In this article, we investigate the binding properties of Topo IV onto DNA in the absence of ATP using a s...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Biophysical Society
2005
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1366538/ https://ncbi.nlm.nih.gov/pubmed/15863484 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.060202 |
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