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Topoisomerase IV Bends and Overtwists DNA upon Binding
Escherichia coli topoisomerase IV (Topo IV) is an essential ATP-dependent enzyme that unlinks sister chromosomes during replication and efficiently removes positive but not negative supercoils. In this article, we investigate the binding properties of Topo IV onto DNA in the absence of ATP using a s...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Biophysical Society
2005
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1366538/ https://ncbi.nlm.nih.gov/pubmed/15863484 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.060202 |
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