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Inducible expression of a degradation-resistant form of p27(Kip1) causes growth arrest and apoptosis in breast cancer cells
The cyclin-dependent kinase (CDK) inhibitor p27(Kip1) (p27) is an important regulator of cell cycle progression controlling the transition from G to S-phase. Low p27 levels or accelerated p27 degradation correlate with excessive cell proliferation and poor prognosis in several forms of cancer. Phosp...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2005
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1366489/ https://ncbi.nlm.nih.gov/pubmed/15996662 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2005.06.012 |
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