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Potential Role of Jun Activation Domain-Binding Protein 1 as a Negative Regulator of p27(kip1) in Pancreatic Adenocarcinoma
Reduced expression of p27 has been associated with poor prognosis in most human cancers, including pancreatic adenocarcinoma. Jun activation domain-binding protein 1 (JAB1), an activator protein (AP-1) coactivator, previously implicated in p27 degradation, is overexpressed in various tumors and corr...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1780177/ https://ncbi.nlm.nih.gov/pubmed/16951171 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-06-0975 |
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