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Simian Virus 40 Small Tumor Antigen Activates AKT and Telomerase and Induces Anchorage-Independent Growth of Human Epithelial Cells

Human keratinocytes immortalized by full-length or early-region simian virus 40 (SV40) DNA grow in agarose and form tumors in nude mice, in contrast to keratinocytes immortalized by the E6/E7 genes of human papillomaviruses. To determine the molecular basis for this biological difference in growth,...

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Bibliografski detalji
Izdano u:J Virol
Glavni autori: Yuan, Hang, Veldman, Tim, Rundell, Kathleen, Schlegel, Richard
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2002
Teme:
Online pristup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136600/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12368310/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.21.10685-10691.2002
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