Simian Virus 40 Small Tumor Antigen Activates AKT and Telomerase and Induces Anchorage-Independent Growth of Human Epithelial Cells

Human keratinocytes immortalized by full-length or early-region simian virus 40 (SV40) DNA grow in agarose and form tumors in nude mice, in contrast to keratinocytes immortalized by the E6/E7 genes of human papillomaviruses. To determine the molecular basis for this biological difference in growth,...

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Bibliografiske detaljer

Udgivet i:	J Virol
Principais autores:	Yuan, Hang, Veldman, Tim, Rundell, Kathleen, Schlegel, Richard
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 2002
Fag:	Transformation and Oncogenesis
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136600/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12368310/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.21.10685-10691.2002
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