Insertions in the Reverse Transcriptase Increase both Drug Resistance and Viral Fitness in a Human Immunodeficiency Virus Type 1 Isolate Harboring the Multi-Nucleoside Reverse Transcriptase Inhibitor Resistance 69 Insertion Complex Mutation

Recent studies have shown that the accumulation of multiple mutations associated with nucleoside reverse transcriptase inhibitor (NRTI) resistance may be grouped as multi-NRTI resistance (MNR) complexes. In this study, we have examined the viral fitness of recombinant viruses carrying the reverse tr...

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Bibliografski detalji
Glavni autori: Quiñones-Mateu, Miguel E., Tadele, Mahlet, Parera, Mariona, Mas, Antonio, Weber, Jan, Rangel, Héctor R., Chakraborty, Bikram, Clotet, Bonaventura, Domingo, Esteban, Menéndez-Arias, Luis, Martínez, Miguel A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2002
Teme:
Vaccines and Antiviral Agents
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC136580/
https://ncbi.nlm.nih.gov/pubmed/12239335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.20.10546-10552.2002
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