Insertions in the Reverse Transcriptase Increase both Drug Resistance and Viral Fitness in a Human Immunodeficiency Virus Type 1 Isolate Harboring the Multi-Nucleoside Reverse Transcriptase Inhibitor Resistance 69 Insertion Complex Mutation

Recent studies have shown that the accumulation of multiple mutations associated with nucleoside reverse transcriptase inhibitor (NRTI) resistance may be grouped as multi-NRTI resistance (MNR) complexes. In this study, we have examined the viral fitness of recombinant viruses carrying the reverse tr...

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Bibliografiske detaljer
Main Authors: Quiñones-Mateu, Miguel E., Tadele, Mahlet, Parera, Mariona, Mas, Antonio, Weber, Jan, Rangel, Héctor R., Chakraborty, Bikram, Clotet, Bonaventura, Domingo, Esteban, Menéndez-Arias, Luis, Martínez, Miguel A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2002
Fag:
Vaccines and Antiviral Agents
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC136580/
https://ncbi.nlm.nih.gov/pubmed/12239335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.20.10546-10552.2002
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