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Mice Deficient in Perforin, CD4(+) T Cells, or CD28-Mediated Signaling Maintain the Typical Immunodominance Hierarchies of CD8(+) T-Cell Responses to Influenza Virus
CD8 T-cell (T(CD8+)) responses elicited by viral infection demonstrate the phenomenon of immunodominance: the numbers of T(CD8+) responding to different viral peptides vary over a wide range in a reproducible manner for individuals with the same major histocompatibility complex class I alleles. To b...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology
2002
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC136568/ https://ncbi.nlm.nih.gov/pubmed/12239309 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.20.10332-10337.2002 |
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