Mice Deficient in Perforin, CD4(+) T Cells, or CD28-Mediated Signaling Maintain the Typical Immunodominance Hierarchies of CD8(+) T-Cell Responses to Influenza Virus

CD8 T-cell (T(CD8+)) responses elicited by viral infection demonstrate the phenomenon of immunodominance: the numbers of T(CD8+) responding to different viral peptides vary over a wide range in a reproducible manner for individuals with the same major histocompatibility complex class I alleles. To b...

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Detalles Bibliográficos

Publicado en:	J Virol
Principais autores:	Chen, Weisan, Bennink, Jack R., Morton, Phillip A., Yewdell, Jonathan W.
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology (ASM) 2002
Assuntos:	Pathogenesis and Immunity
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136568/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12239309/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.20.10332-10337.2002
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