A Prenylation Inhibitor Prevents Production of Infectious Hepatitis Delta Virus Particles

Hepatitis delta virus (HDV) causes both acute and chronic liver disease throughout the world. Effective medical therapy is lacking. Previous work has shown that the assembly of HDV virus-like particles (VLPs) could be abolished by BZA-5B, a compound with farnesyltransferase inhibitory activity. Here...

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發表在:	J Virol
Principais autores:	Bordier, Bruno B., Marion, Patricia L., Ohashi, Kazuo, Kay, Mark A., Greenberg, Harry B., Casey, John L., Glenn, Jeffrey S.
格式:	Artigo
語言:	Inglês
出版:	American Society for Microbiology (ASM) 2002
主題:	Vaccines and Antiviral Agents
在線閱讀:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136538/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12239323/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.20.10465-10472.2002
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