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Replication of a Cytopathic Strain of Bovine Viral Diarrhea Virus Activates PERK and Induces Endoplasmic Reticulum Stress-Mediated Apoptosis of MDBK Cells

Endoplasmic reticulum (ER) stress signaling is an adaptive cellular response to the loss of ER Ca(2+) homeostasis and/or the accumulation of misfolded, unassembled, or aggregated proteins in the ER lumen. ER stress-activated signaling pathways regulate protein synthesis initiation and can also trigg...

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Udgivet i:J Virol
Principais autores: Jordan, Robert, Wang, Lijuan, Graczyk, Thomas M., Block, Timothy M., Romano, Patrick R.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2002
Fag:
Virus-Cell Interactions
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136515/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12208938/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.19.9588-9599.2002
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