Replication of a Cytopathic Strain of Bovine Viral Diarrhea Virus Activates PERK and Induces Endoplasmic Reticulum Stress-Mediated Apoptosis of MDBK Cells

Endoplasmic reticulum (ER) stress signaling is an adaptive cellular response to the loss of ER Ca(2+) homeostasis and/or the accumulation of misfolded, unassembled, or aggregated proteins in the ER lumen. ER stress-activated signaling pathways regulate protein synthesis initiation and can also trigg...

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Bibliographic Details
Main Authors: Jordan, Robert, Wang, Lijuan, Graczyk, Thomas M., Block, Timothy M., Romano, Patrick R.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2002
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC136515/
https://ncbi.nlm.nih.gov/pubmed/12208938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.19.9588-9599.2002
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