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Activation of Terminally Differentiated Human Monocytes/Macrophages by Dengue Virus: Productive Infection, Hierarchical Production of Innate Cytokines and Chemokines, and the Synergistic Effect of Lipopolysaccharide

Dengue virus (DV) primarily infects blood monocytes (MO) and tissue macrophages (Mφ). We have shown in the present study that DV can productively infect primary human MO/Mφ regardless of the stage of cell differentiation. After DV infection, the in vitro-differentiated MO/Mφ secreted multiple innate...

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Bibliografische gegevens
Hoofdauteurs: Chen, Yun-Chi, Wang, Sheng-Yuan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2002
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC136495/
https://ncbi.nlm.nih.gov/pubmed/12208965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.19.9877-9887.2002
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