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Maturation of Dengue Virus Nonstructural Protein 4B in Monocytes Enhances Production of Dengue Hemorrhagic Fever-Associated Chemokines and Cytokines
High levels of viremia and chemokines and cytokines underlie the progression of severe dengue disease. Dengue virus (DENV) preferentially infects peripheral blood monocytes, which secrete elevated levels of immunomediators in patients with severe disease. Further, DENV nonstructural proteins (NS) ar...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3184475/ https://ncbi.nlm.nih.gov/pubmed/21810535 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2011.07.006 |
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