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Activation of Terminally Differentiated Human Monocytes/Macrophages by Dengue Virus: Productive Infection, Hierarchical Production of Innate Cytokines and Chemokines, and the Synergistic Effect of Lipopolysaccharide
Dengue virus (DV) primarily infects blood monocytes (MO) and tissue macrophages (Mφ). We have shown in the present study that DV can productively infect primary human MO/Mφ regardless of the stage of cell differentiation. After DV infection, the in vitro-differentiated MO/Mφ secreted multiple innate...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC136495/ https://ncbi.nlm.nih.gov/pubmed/12208965 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.19.9877-9887.2002 |
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