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Formation and elimination of sulphamethoxazole hydroxylamine after oral administration of sulphamethoxazole.

The formation and elimination of sulphamethoxazole hydroxylamine in relation to the pharmacokinetics of the parent compound and its N4-acetyl metabolite were investigated in six healthy subjects after a single oral dose of 800 mg sulphamethoxazole. The apparent half-lives of sulphamethoxazole and it...

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Bibliografische gegevens
Hoofdauteurs: van der Ven, A J, Mantel, M A, Vree, T B, Koopmans, P P, van der Meer, J W
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1994
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1364861/
https://ncbi.nlm.nih.gov/pubmed/7981016
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