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Urinary recovery and kinetics of sulphamethoxazole and its metabolites in HIV-seropositive patients and healthy volunteers after a single oral dose of sulphamethoxazole.

1. The urinary excretion of sulphamethoxazole and its metabolites was compared between healthy volunteers and HIV-seropositive patients in order to get a better understanding of why HIV seropositives are more predisposed to idiosyncratic toxicity of sulphonamides. 2. A single 800 mg oral dose of sul...

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Detalhes bibliográficos
Main Authors: van der Ven, A J, Vree, T B, van Ewijk-Beneken Kolmer, E W, Koopmans, P P, van der Meer, J W
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1365073/
https://ncbi.nlm.nih.gov/pubmed/7654479
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