Reduced startle gating after D1 blockade: Effects of concurrent D2 blockade

BACKGROUND: Prefrontal D1 systems have been implicated in the regulation of working memory and in the pathophysiology of schizophrenia. D1 hypofunction might contribute to reduced sensorimotor gating in schizophrenia patients since D1 activity in the medial prefrontal cortex (MPFC) regulates prepuls...

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Autores principales: Swerdlow, Neal R., Shoemaker, Jody M., Bongiovanni, Michele J., Neary, Alaina C., Tochen, Laura S., Saint Marie, Richard L.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2005
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1364453/
https://ncbi.nlm.nih.gov/pubmed/16188305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbb.2005.08.018
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